Research

He Q, Zhong J, Li H, Li X, Shi Y, et al. · RSC Advances

Composite lateral-flow substrate made by capillary deposition of cellulose onto OSTE synthetic paper, giving uniform, adjustable lateral flow.

Keulen J, Zhong Y, Dangel L, Youhanna S, Zandi Shafagh R, et al. · Advanced Science

Machine-vision-guided microphysiological platform with automated microfluidics; chips are micro-RIM-molded from OSTEMER 322 to avoid drug sorption artefacts.

Rodríguez-Ruiz I, Moya-Garrido P, Risso VA, Martínez-Rodríguez S, Teychené S, et al. · Nanoscale Advances

Flow-through β-lactam antibiotic sensor based on cross-linked crystals of an ancestral β-lactamase packed in injection-molded OSTEMER 322 chips.

Amorim J, Vesalainen L, Dreano L, Haapala M, Cruz CD, et al. · Advanced Materials Interfaces

BioEISense: flow-through biofilm channel of OSTE and PDMS with impedance sensing for real-time monitoring of S. aureus biofilms and antibiofilm agents.

Jiang H, Derisoud E, Parreira D, Taebnia N, Jannig PR, et al. · Advanced Science

Placental study using multilayer OSTE+/PMMA/PDMS microfluidic devices to coculture trophoblast organoids with adipose spheroids.

Ruska R, Zutis E, Tars K, Kazaks A, Paidere G, et al. · Analytical Methods

Synthesizes and tests a new linker that overcomes air oxidation of surface thiols, increasing protein binding inside OSTE microfluidic devices.

Zandi Shafagh R, Kaveh J, Lauschke VM · Chemistry–Methods

In-mold wettability patterning: micro-RIM of OSTE+ against multi-material molds structures open and closed microfluidics and patterns wettability without extra monomers or back-end treatment.

Senthilkumar A · MSc thesis, KTH Royal Institute of Technology

KTH MSc thesis comparing adhesion of recombinant spider-silk nanomembranes to structural substrates, including OSTE with varied surface chemistries, for light-sail applications.

Marrero D, Pujol-Vila F, Tuset E, Gabriel G, Villa R, et al. · Lab on a Chip

Low-temperature inkjet-printed electrochemical sensors on OSTE+ microfluidics exploit the polymer's thiols for metal adhesion and its oxygen scavenging for local oxygen control in organ-on-chip devices. A bioRxiv preprint precedes it.

Zhang X, Wang Z, Qu X, Wang Y, Zhu G, et al. · Advanced Materials Technologies

Intracellular delivery platform with a piezoelectric vibrator and nanoneedle chips whose microchannels are made from pattern-bonded OSTE.

Keulen J · Doctoral thesis, Karolinska Institutet

Karolinska thesis on multi-organ microphysiological systems built around a pneumatically actuated OSTE+ platform that keeps PDMS and PMMA outside the fluid path.

Guo W, Xiao Z, Feng Z, Zhong J, Ye Z, et al. · Materials Today Communications

Dedicated review of OSTE microfluidics: curing chemistry, surface and mechanical properties, permeability, biocompatibility, oxygen scavenging, fabrication methods and applications.

Li H, Zhong J, He Q, Zhang H, Ting Chu L, et al. · Small Methods

Superhydrophobic OSTE synthetic paper keeps a stable underwater air plastron that is replenished by capillary air transport within sub-second timescales.

Mäenpää J · MSc thesis, Aalto University

Aalto MSc thesis developing OSTEMER 322 chips with sub-micron traps for single-bacteria studies as a non-absorbing PDMS alternative.

Padilla AE, Jones M, Joddar B · RSC Advances

MEA-integrated tissue chip cast in OSTEMER 322 used to measure human neuronal network damage after gamma irradiation.

Orban G, Perna A, Vincenzi M, Adamo R, Angotzi GN, et al. · Micromachines

Die-level MEMS post-processing of CMOS neural probes; bonded wires and PCB area are encapsulated with OSTEMER 322 for mechanical and biological protection.

Naveen Kumar KR, Hamid S, Niketa AK, Prajapati E, Kumar S · Lab on a Chip

Develops membrane-valved microfluidics made entirely from Ostemers, reporting ~200 ms switching comparable to PDMS valves plus long-term stability in thin flexible devices and in chemically aggressive media.

Kwon M, Seo D, Kim T · ACS Nano

Hybrid PDMS/OSTEMER chips in which the modulus mismatch preserves nanoscale wrinkles as nanochannels, producing tunable ionic memristors. A MEMS 2026 conference version exists.

Borrego EA, Perez JL, Esparza A, Delgado P, Moreno K, et al. · Discover Applied Sciences

Multi-tissue microphysiological system for anticancer and cardiotoxicity screening, fabricated from OSTEMER 322.

Amorim J, Rosqvist E, Cruz CD, Haapala M, Peltonen J, et al. · Advanced Materials Interfaces

Systematic study of Staphylococcus aureus biofilm formation on OSTE compositions, toward flow-through microfluidic biofilm models.

Padilla AE, C G, Hovell C, Mares J, Reumers V, et al. · npj Microgravity

MEA-integrated 3D neuronal culture device cast in OSTEMER 322 for electrophysiology under simulated microgravity.

Pujol‐Vila F, Casas‐Aguilera E, Alvarez M · Advanced Optical Materials

Bilayer PDMS/OSTE+ mechanochromic cantilevers bend in opposite directions for different VOCs, enabling color-based VOC discrimination.

Rautsola I · Doctoral thesis, University of Helsinki

Helsinki PhD thesis validating OSTE micropillar HLM chips for drug-drug interaction and metabolism studies.

Abouhagger A, Andriukonis E, Grigorianaite G, da Silva RR, Kasperaviciute K, et al. · ACS Omega

PDMS-free OSTE/COC chip with five chambers for biofilm cultivation and analysis under controlled flow.

He Q, Zhong J, Li H, Ye Z, Zhang M, et al. · 2025 IEEE 20th International Conference on Nano/Micro Engineered and Molecular Systems (NEMS)

Wood-ear-like wicking substrate: cellulose self-assembled on an OSTE microneedle array produces fast lateral liquid imbibition.

Jash M, Lu X, Zhou J, Toprak MS, Sychugov I · Advanced Optical Materials

Au-Ag nanoclusters polymerized into OSTE transform in situ, giving near-infrared emission with quantum yields above 70%.

Li M, Feng M, Wang J, Zhang J, Ren L, Zhang P · Journal of Physics: Conference Series

Graphene oxide covalently incorporated into OSTE yields composites with tunable dielectric properties and good thermal stability.

Angotzi GN, Vöröslakos M, Perentos N, Ribeiro JF, Vincenzi M, et al. · Advanced Science

Describes 1024-channel active CMOS neural probes; OSTEMER 322 Crystal Clear is used to encapsulate and protect the wire bonds.

Kemas A · Doctoral thesis, Karolinska Institutet

Karolinska thesis on in vitro models for MASLD drug development, including the compound-absorption comparison of device polymers and OSTE+-based systems.

Zhang M, Li H, Li X, Ye Z, He Q, et al. · Biosensors

A Parylene-C coating passivates the thiol groups of OSTE master molds so that PDMS can be cured against them; the resulting PDMS pillar and well arrays were used for plasma separation and polymorphic crystallization.

Wang J, Li M, Feng M, Ren L, Zhang P, Jiang L · Second International Academic Conference on Optics and Photonics (IACOP 2024)

Carbon quantum dots co-doped with gold nanoparticles in OSTE show enhanced, excitation-dependent photoluminescence.

Šints V, Cīmurs J, Birjukovs M, Driķis I, Goluba K, et al. · PLOS One

Models serum-supplemented medium flow (non-constant viscosity) for accurate shear stress in organ-on-chip devices made of OSTE and COC.

Ota S, Yasuga H, Akagawa T, Kurashina Y, Nakazawa K, Kikuchi S · Biotechnology and Bioengineering

Single-cell manipulation with magnetic forces at the edge of transparent, low-autofluorescence OSTE plates; studies how plate geometry scales the effect.

Das S, Patnaik A, Singh A, Rao VR, Kundu T · Journal of Lightwave Technology

Thiol-ene-epoxy planar waveguides used as refractometric sensors with prism coupling and a low-cost CCD readout.

Panuška P, Smejkal J, Štofik M, Žmudová Z, Španbauerová K, et al. · BioChip Journal

OSTE+ droplet microfluidic system that forms, cultivates and handles uniform tumour spheroids for drug screening.

Feng Z, Chen G, Chen Z, Ni K, Yang J, et al. · 2024 IEEE 19th International Conference on Nano/Micro Engineered and Molecular Systems (NEMS)

Photolithographic OSTE wells sealed with an ultrathin OSTE layer store liquid samples down to ~14 nL with resistance to evaporation; release is by capillary-tube puncture.

Chae Y, Bae J, Kim T · RSC Advances

Flexible through-hole molds with an OSTEMER layer on a PDMS frame pattern liquid materials (e.g. perovskites, resists) on flat and curved substrates.

Raja SN, Jain S, Kipen J, Jaldén J, Stemme G, et al. · ACS Applied Materials & Interfaces

Electromigrated gold nanogap tunnel-junction arrays operated in liquids; a 12-channel OSTEMER 322 flow cell bonded to the chip was chosen for its solvent resistance and negligible swelling.

Zhang Y, Zheng Z, Gan Z, Huang R, Zhang X · Small Science

Rubrene-derivative/OSTE hybrids made by thiol-ene click chemistry give bright, photostable, Stokes-shifted emission for flexible LSC-integrated photovoltaics.

Wu Y, Huang J, Zang J, Zhou J, Cheng C, et al. · Energy & Environmental Science

An off-stoichiometric thiol-ene matrix red-shifts CuInS2/ZnS quantum-dot emission, enlarging the Stokes shift and giving a certified record efficiency for a large luminescent solar concentrator.

Rautsola I, Haapala M, Huttunen L, Korhonen O, Sikanen T · Lab on a Chip

Freeze-drying extends by months the shelf life of human liver microsome chips built on off-stoichiometric thiol-ene pillar arrays.

Böcherer D, Li Y, Rein C, Franco Corredor S, Hou P, Helmer D · Advanced Functional Materials

First high-resolution 3D printing of a dual-curing off-stoichiometric thiol-ene/epoxy resin, producing enclosed microchannels of tens of microns without clogging for bioassay devices.

Bakute N, Andriukonis E, Kasperaviciute K, Dobilas J, Sapurov M, et al. · Scientific Reports

OSTE microphysiological chip with integrated electrodes for pulsed electric fields and TEER, plus in-situ pH and oxygen monitoring, replacing PDMS for chemical and mechanical robustness.

Liu Y, Li H, Feng Z, Chen Z, Zhang M, et al. · 2024 IEEE 19th International Conference on Nano/Micro Engineered and Molecular Systems (NEMS)

Hollow OSTE microneedle arrays made by diffraction lithography and coupled to a PDMS finger-pump chip for liquid sampling and delivery.

Li H, Zhang M, Liu Y, Yu S, Li X, et al. · Micromachines

Two-step OSTE lithography builds 'micro mushroom forest' structures that create superhydrophobic substrates bottom-up.

Ruska R, Sarakovskis A, Zutis E, Paidere G, Vozny I, et al. · Materials

Raman and XPS study of how thiol groups on OSTE surfaces bind, using gold nanoparticles and new linkers to improve surface functionalization for microfluidics.

Aubrecht P, Smejkal J, Panuška P, Španbauerová K, Neubertová V, et al. · RSC Advances

Systematic biocompatibility study of OSTEMER 322 and surface-modified variants across several cell types, supporting its use in cell-based microfluidics.

Goluba K, Parfejevs V, Rostoka E, Jekabsons K, Blake I, et al. · Materials Today Bio

Personalized pancreatic cancer chip with a functional endothelial barrier for tumour biomarker detection, built from OSTE 322 and COC.

Zhang H, Ye M, Li W, Zhang Y, Sheng Y, Zhang X · Optics Express

Adding gold nanoparticles to CdSe/ZnS quantum dots in OSTE boosts absorption and emission through plasmonic effects in luminescent solar concentrators.

Harris P, Kaveh J, Kemas AM, Mikaelsson H, Fielden M, et al. · Advanced Materials Interfaces

Shows robust direct bonding of OSTE+ to a range of thermoplastics and glass (up to 1.5 MPa, improved further by priming) to build hybrid chips suitable for drug studies.

Pujol-Vila F, Álvarez M · Eurosensors 2023

Conference paper introducing soft optomechanical colorimetric devices made from OSTE, exploiting its intrinsic redox activity.

Guthmann M, Qian C, Gialdini I, Nakatani T, Ettinger A, et al. · Genes & Development

Developmental biology study of heterochromatin in mouse embryos; OSTEMER 322 is used to make the well layer of the embryo imaging chamber (minor, supporting role).

Kemas AM, Zandi Shafagh R, Taebnia N, Michel M, Preiss L, et al. · Advanced Healthcare Materials

Fabricates identical devices from eight polymers, including OSTEMER 322, and shows that drug absorption into device materials such as PDMS can distort preclinical safety readouts.

Ju X · Doctoral thesis (France, theses.fr)

French PhD thesis developing an OSTE resin for two-photon polymerization with tunable surface alkene excess, grafted with PEG and proteins to build bioactive 3D microstructures.

Borda E, Medagoda DI, Airaghi Leccardi MJI, Zollinger EG, Ghezzi D · Biomaterials

Conformable multilayer micro-ECoG arrays manufactured in OSTE+ by standard cleanroom processes, exploiting low modulus and dry bonding. A bioRxiv preprint exists.

Esparza A, Jimenez N, Joddar B, Natividad-Diaz S · SN Applied Sciences

3D cardiovascular tissue models cultured in capillary-circuit microfluidic devices cast from OSTEMER 322.

Zhang M, Li H, Xiao Z, Feng Z, Yu S, et al. · 2023 IEEE 18th International Conference on Nano/Micro Engineered and Molecular Systems (NEMS)

Backside lithography of OSTE through a diffusing glass produces convex microstructures that are then replicated into gelatin or agarose to obtain concave microwells and channels for micro-tissue work.

Yang Y, Xiao Z, Sun L, Feng Z, Chen Z, Guo W · Micromachines

Hybrid microneedle patches with drug-loaded silk fibroin tips replica-molded onto an OSTE base.

Cherian D, Roy A, Bersellini Farinotti A, Abrahamsson T, Arbring Sjöström T, et al. · Advanced Healthcare Materials

Flexible organic electronic ion pump for drug delivery, encapsulated and patterned with OSTEMER 221 after priming with Mercene's PX15 surface modifier.

Puchnin K, Ryazantsev D, Latipov E, Grudtsov V, Kuznetsov A · Polymers

Follow-up introducing allylsilane anchor groups (OSTE-AS) for adhesive-free bonding to silicon, with optimized hardness, tensile strength, dielectric and optical properties and spin-coated thin layers.

Das S, Singh A, Rao VR, Kundu T · ACS Applied Polymer Materials

Tunes tetra-thiol content in OSTE+ films and correlates elastic modulus with optical properties to build plasmonic sensing platforms.

Zhou Y, Jönsson A, Sticker D, Zhou G, Yuan Z, et al. · Analytical and Bioanalytical Chemistry

Dual-function thiol-ene microchip made from an off-stoichiometric emulsion performs online digestion and glycopeptide enrichment of inflammation-related proteins.

Sønstevold L, Yadav M, Arnfinnsdottir NB, Herbjørnrød AK, Jensen GU, et al. · Journal of Micromechanics and Microengineering

Develops a UVA-initiated bonding process for a commercial two-step-curable OSTE+ that attaches rigid microfluidic cartridges to antibody-functionalized silicon ring-resonator sensors without destroying their bioactivity.

Zandi Shafagh R, Youhanna S, Keulen J, Shen JX, Taebnia N, et al. · Advanced Science

Pancreas-liver coculture chip assembled from OSTE+ (OSTEMER 322), PMMA and PDMS parts reveals human metabolic crosstalk relevant to hyperglycemia.

Feng Z, Xiao Z, Sun L, Yang Y, Guo W · 2022 IEEE 35th International Conference on Micro Electro Mechanical Systems Conference (MEMS)

Aqueous replica molding: OSTE is cured on patterned glycerol-water droplets on PDMS to rapidly make hemispherical wells and semicylindrical channels with round cross-sections.

Hermans L, Kaynak M, Braun J, Ríos VL, Chen CL, et al. · Nature Communications

Microengineered implants made from OSTEMER 220 enable long-term imaging of the ventral nerve cord in behaving adult Drosophila.

Struyfs C, Breukers J, Spasic D, Lammertyn J, Cammue BPA, Thevissen K · International Journal of Molecular Sciences

PEG-grafted OSTE+ microwell arrays for continuous single-yeast-cell analysis reveal the mode of action of an antifungal plant defensin.

Puchnin K, Ryazantsev D, Grudtsov V, Golubev Y, Kuznetsov A · Polymers

Adds mercaptosilane to OSTE formulations (OSTE-MS) so the polymer bonds directly to silicon wafers without adhesion promoters; mechanical, optical, thermal and chemical properties are characterized for on-chip packaging.

Chae Y, Bae J, Lim K, Kim T · RSC Advances

Transparent conductive grids printed on curved substrates using flexible template molds whose stiff layer is made from OSTEMER 322.

Das S, Singh A, Rao VR, Kundu T · Journal of Materials Chemistry C

Planar photodetectors made from OSTE+ with varied monomer ratios show light-intensity-dependent photoresponse.

Guo W, Hansson J, Gustafsson L, van der Wijngaart W · 2021 IEEE 34th International Conference on Micro Electro Mechanical Systems (MEMS)

'Bend-and-bond' origami: partially cured OSTE+ sheets are patterned, folded into 3D shapes and then thermally cured so that touching surfaces bond spontaneously, giving inert folded microstructures.

Matthiesen I, Voulgaris D, Nikolakopoulou P, Winkler TE, Herland A · Small

Isogenic hiPSC blood-brain-barrier chip built in OSTE+ with continuous barrier-integrity sensing (<2 min resolution), used to study nitrosative stress and antioxidant protection. A bioRxiv preprint exists.

Xiao Z, Yang Y, Zhang X, Guo W · Micromachines

Covering lateral-flow substrates (nitrocellulose and OSTE synthetic paper) with tape is shown to be a simple way to tune capillary flow rate.

Yasuga H, Iseri E, Wei X, Kaya K, Di Dio G, et al. · Nature Physics

Shows that passing two immiscible fluids through OSTE micropillar scaffolds (synthetic-paper-type) spontaneously creates 3D periodic droplet lattices (FLUID3EAMS). OSTE use confirmed via the authors' later review.

Xiao Z, Sun L, Yang Y, Feng Z, Dai S, et al. · Biosensors

Passive plasma separation combining a filtration membrane with a hydrophilic OSTE 'pillar forest' capillary pump made by double replica molding from laser-cut PMMA.

Kiiski IMA · Doctoral thesis, University of Helsinki

Helsinki PhD thesis on immobilized enzyme microreactors fabricated from OSTE for drug-metabolism research.

Kuusisto E, Heikkinen JJ, Järvinen P, Sikanen T, Franssila S, Jokinen V · Sensors and Actuators B: Chemical

Inkjet-printed flexible silver electrodes on thiol-ene compositions from 30% thiol to 5% allyl excess, with resistivity down to 30 µΩcm and good adhesion.

Kemas AM, Youhanna S, Zandi Shafagh R, Lauschke VM · The FASEB Journal

Sensitive glucose-oxidase assay for 3D liver cultures; the enzymes are covalently bound via thiol-Michael chemistry to reaction-injection-molded OSTE chips.

Rimsa R, Galvanovskis A, Plume J, Rumnieks F, Grindulis K, et al. · Micromachines

Tests OSTE for lung-on-chip prototyping versus PDMS: light transmission, small-molecule and dye absorption, enzymatic inhibition and membrane integration.

Yang Y, Xiao Z, Sun L, Dai S, Yang H, et al. · Conference paper (deposited on Zenodo, 2021)

Conference paper on making OSTE pillar forests by double replica molding of laser-cut PMMA molds in under three hours, with tunable pillar pitch and capillary flow rate.

Currie C, Gray BL · 2021 IEEE 16th Nanotechnology Materials and Devices Conference (NMDC)

OSTEMER 324 Flex filled with 25 wt% rare-earth magnet powder stays flexible and photopatternable and can be permanently magnetized for bidirectional microfluidic actuators.

Esposito TVF, Stütz H, Rodríguez-Rodríguez C, Bergamo M, Charles L, et al. · ACS Biomaterials Science & Engineering

Flow-focusing chips made with off-stoichiometry thiol-ene chemistry, featuring a heated curing channel, produce size-controlled heat-denatured macroaggregated albumin microparticles with much lower dispersity than bulk methods.

Guo W, Hansson J, van der Wijngaart W · 2021 IEEE 16th International Conference on Nano/Micro Engineered and Molecular Systems (NEMS)

Integrates a colorimetric glucose assay on OSTE synthetic paper for quantitative blood-glucose measurement in a lateral-flow format.

Farjana S, Ghaderi M, Zaman AU, Rahiminejad S, Eriksson T, et al. · Journal of Infrared, Millimeter, and Terahertz Waves

Journal version of the 140 GHz gap-waveguide antenna: its three layers are made by SU-8 processing, PDMS molding and injection molding of OSTEMER, followed by gold coating.

Winkler TE, Herland A · ACS Applied Materials & Interfaces

First perfused-condition study of small-molecule sorption in microfluidic materials: PDMS absorbs neuropsychopharmaca strongly, while OSTE+ and tape/polycarbonate laminates perform much better. A bioRxiv preprint exists.

Kiiski I, Järvinen P, Ollikainen E, Jokinen V, Sikanen T · Lab on a Chip

Exploits OSTE's oxygen scavenging to set physiologically low oxygen in microfluidic liver-microsome reactors for drug-metabolism assays under hypoxia, and studies the scavenging mechanism.

Breukers J, Horta S, Struyfs C, Spasic D, Feys HB, et al. · ACS Applied Materials & Interfaces

PEG grafting on OSTE+ microwell arrays reduces nonspecific cell adhesion so single cells can be retrieved efficiently with optical tweezers.

Kratz SRA, Bachmann B, Spitz S, Höll G, Eilenberger C, et al. · Scientific Reports

Presents a 3D-printed compression test device for bond strength and uses it to compare bonding strategies for biochip materials, including tensile and shear strength of OSTEMER 322 bonded to various substrates.

Sathyanarayanan G, Haapala M, Dixon C, Wheeler AR, Sikanen TM · Advanced Materials Technologies

Interfaces digital microfluidics with channel-based separations using inkjet-printed silver electrodes and UV-cured thiol-enes as dielectric and structural layers.

Gavira JA, Rodriguez-Ruiz I, Martinez-Rodriguez S, Basu S, Teychené S, et al. · Acta Crystallographica Section D Structural Biology

Low-cost X-ray-transparent counter-diffusion microchips (OSTEMER channels combined with thin films) allow in situ protein crystallization and room-temperature data collection at ~1 Å resolution.

Das S, Patnaik A, Rao VR, Kundu T · Organic Photonic Materials and Devices XXII

Multimode planar waveguides made by photolithography of OSTE+ thin films, used for evanescent-wave absorption refractive-index sensing.

Sathyanarayanan G · Doctoral thesis, University of Helsinki

Helsinki PhD thesis on digital microfluidics for drug metabolism, introducing OSTE as dielectric and interfacing material for inkjet-printed DMF.

Hu Y, Shu J, Zhang X, Zhao A, Liu Y, et al. · Journal of Luminescence

Incorporates lead-halide perovskite nanocrystals into OSTE for solid-state emitters and studies how encapsulation alters their electronic transitions.

Zandi Shafagh R, Shen JX, Youhanna S, Guo W, Lauschke VM, et al. · ACS Applied Bio Materials

Nanoimprint lithography of OSTE+ gives robust, directly biofunctionalized high-aspect-ratio nanopillars (down to 100 nm) and holes for studying human cell biomechanics.

Guo W, Vilaplana L, Hansson J, Marco MP, van der Wijngaart W · Biosensors and Bioelectronics

Thiol-ene synthetic paper used as a solid substrate for immunoassays gives a stronger fluorescence signal than glass or nitrocellulose.

Hoffmann C, Grey C, Pinelo M, Woodley JM, Daugaard AE, Adlercreutz P · ChemPlusChem

β-Glucosidase immobilized on functionalized OSTE particles; imidazole and carboxylic-acid microenvironments raise trans-glycosylation selectivity two- to three-fold.

Kamiya H, Yasuga H, Miki N · PLOS ONE

Synthetic microfluidic paper made from OSTEMER 220 Litho is used to sample precise liquid volumes for ion-concentration measurement in body fluids.

Currie C · MSc thesis, Simon Fraser University

SFU thesis on magnetic composite membrane actuators, including an injection-moldable OSTE+ resin loaded with rare-earth magnet particles.

Krenger R, Cornaglia M, Lehnert T, Gijs MAM · Lab on a Chip

C. elegans culture chip made from low-gas-permeability OSTE+ with integrated luminescent oxygen sensing to measure the oxygen consumption rate of single worms.

Bourg S, d’Orlyé F, Griveau S, Bedioui F, Fracassi da Silva JA, Varenne A · Chemosensors

Compares direct UV-initiated and other strategies for immobilizing thiol-modified aptamers on OSTE surfaces, enabling multiple modified zones in one open microchannel for analyte extraction.

Lange T, Charton S, Bizien T, Testard F, Malloggi F · Lab on a Chip

Assesses OSTE+ for small-angle X-ray scattering and builds an X-ray-compatible OSTE+ droplet chip for in situ SAXS monitoring of reactions.

Esquibel CR, Wendt KD, Lee HC, Gaire J, Shoffstall A, et al. · Frontiers in Neuroscience

Second-harmonic-generation imaging of collagen around chronically implanted electrodes, including OSTE+ probes of hard and soft formulations.

Guo W · Doctoral thesis, KTH Royal Institute of Technology

Guo's KTH PhD thesis on OSTE synthetic paper for point-of-care tests: capillary flow control, surface modification, plasma separation and immunoassays.

Guo W, Hansson J, van der Wijngaart W · Analytical Chemistry

Plasma separation on OSTE synthetic paper by local agglutination of blood cells and capillary wicking, with surface treatments studied to minimize protein loss.

Sticker D, Geczy R, Häfeli UO, Kutter JP · ACS Applied Materials & Interfaces

Review of thiol-ene polymers (including off-stoichiometric formulations) as microfluidic materials for organs-on-chip, droplets, microanalytics and point-of-care tests.

Huang J, Zhou J, Haraldsson T, Clemments A, Fujii M, et al. · Solar RRL

Luminescent solar concentrators made as triplex glass laminates of Si quantum dots in OSTE, which improves the dots' quantum yield.

Steinegger A, Borisov SM · ACS Omega

Optical thermometers based on Zn(II) Schiff-base TADF emitters; an oxygen-consuming OSTE top layer removes oxygen cross-sensitivity.

Urucu OA, Aracier ED, Çakmakçi E · Microchemical Journal

Photocured OSTE discs containing allylimidazole act as sorbents that selectively and efficiently remove gold(III) from aqueous solutions.

Hong T, Liu W, Li M, Chen C · The Analyst

Review of click chemistry in microscale systems that highlights OSTE microchips alongside bio-functionalized and monolithic microsystems.

Guo M · Doctoral thesis, KTH Royal Institute of Technology

KTH thesis on digital electrical DNA sensing with a gold-coated porous membrane detector sandwiched between off-stoichiometric thiol-ene-epoxy layers.

Bastiaens A, Frimat JP, van Nunen T, Luttge R · Journal of Vacuum Science & Technology B, Nanotechnology and Microelectronics: Materials, Processing, Measurement, and Phenomena

Nanogrooved culture substrates for brain-on-chip models: a replication protocol produces nanogrooves in PDMS and Ostemer, and nanogrooved Ostemer is shown to replicate faithfully for neuronal cultures.

Liberti M · MSc thesis, Politecnico di Torino

Politecnico di Torino MSc thesis on fabrication and mechanical characterization of self-opening intraneural OSTE+ electrodes for optic nerve stimulation.

Tähkä S, Sarfraz J, Urvas L, Provenzani R, Wiedmer SK, et al. · Analytical and Bioanalytical Chemistry

Replica-molded high-aspect-ratio thiol-ene micropillar reactors whose excess surface thiols bind gold nanoparticles carrying α-chymotrypsin for on-chip proteolysis.

Krenger RP · Doctoral thesis, EPFL

EPFL PhD thesis on microfluidic and MEMS tools for C. elegans, including the OSTE+ oxygen-consumption platform.

El Fissi L, Fernández R, García P, Calero M, García JV, et al. · Sensors and Actuators A: Physical

Uses OSTEMER as a rapid encapsulation/packaging material for electronics and microfluidics on printed circuit boards (liquid-biopsy sensor project). Only the title and funding note were accessible; details not confirmed.

Han H · MSc thesis, Politecnico di Torino

MSc thesis (Politecnico di Torino) optimizing a robotic C. elegans culture/imaging platform, including a 3D-molding process for its OSTE+ chips.

Sticker D, Rothbauer M, Ehgartner J, Steininger C, Liske O, et al. · ACS Applied Materials & Interfaces

Adapts an off-stoichiometric thiol-ene-epoxy to scavenge dissolved oxygen for weeks, creating tunable hypoxic conditions in cell-culture biochips without external gas control. A MicroTAS 2017 conference version exists.

Liu L, Deng L, Huang S, Zhang P, Linnros J, et al. · The Journal of Physical Chemistry Letters

Single-dot spectroscopy separates oxygen-assisted and oxygen-free photodegradation paths in perovskite nanocrystals and shows OSTE encapsulation suppresses photo-etching.

Farjana S, Rahiminejad S, Zaman AU, Hansson J, Ghaderi MA, et al. · 2019 IEEE MTT-S International Microwave Workshop Series on Advanced Materials and Processes for RF and THz Applications (IMWS-AMP)

Fabricates a 140 GHz gap-waveguide planar array antenna for MIMO backhaul using SU-8, PDMS molding and injection-molded OSTEMER layers coated with gold.

Lange T · Doctoral thesis, Université Paris-Saclay (theses.fr)

French PhD thesis on confined precipitation in droplets, including characterization of OSTE+ for SAXS and an OSTE+ chip for in situ studies.

Zandi Shafagh R, Decrop D, Ven K, Vanderbeke A, Hanusa R, et al. · Microsystems & Nanoengineering

Micro-reaction injection molding simultaneously structures and surface-energy-patterns OSTE, producing arrays of ~1.8 million hydrophilic-in-hydrophobic femtolitre wells for digital assays.

Sathyanarayanan G, Haapala M, Kiiski I, Sikanen T · Analytical and Bioanalytical Chemistry

Digital microfluidic cytochrome P450 reactors using porous off-stoichiometric thiol-ene monolith plugs and inkjet-printed heaters for droplet-scale drug metabolism.

Zandi Shafagh R, Vastesson A, Guo W, van der Wijngaart W, Haraldsson T · ACS Nano

Uses thiol-ene as an electron-beam lithography resist whose native surface thiols allow direct 'click' immobilization of biomolecules on the written nanostructures.

Zhou XC, Haraldsson T, Nania S, Ribet F, Palano G, et al. · Advanced Functional Materials

Introduces a thiol-ene-based material and one-step UV process that forms core-shell microbeads (PEG hydrogel core, nanoporous solid shell) to encapsulate human cells with controlled morphology.

Romulus P · MSc thesis, KTH Royal Institute of Technology

MSc thesis integrating anodized nanoporous alumina with photolithographically made OSTE microwells as a platform for single-bacterium antibiotic susceptibility testing.

Vastesson A, Guo M, Haraldsson T, van der Wijngaart W · Sensors and Actuators B: Chemical

Polymer nanolitre well arrays sealed with gold films store liquids and release them on demand by rapid electrochemical opening of the gold membrane (journal follow-up of the liquid-storage work).

Malmström J · MSc thesis, Uppsala University

MSc thesis (Uppsala) designing a high-pressure lab-on-chip for photonic single-cell sensing, using OSTE for fabrication and evaluating its fluorescence transparency.

Kamiya H, Otsuki H, Ota T, Yasuga H, Miki N · The Proceedings of the Symposium on Micro-Nano Science and Technology

Sampling strip with slanted interlocked OSTE micropillars for accurate collection of small liquid volumes, aimed at monitoring blood potassium.

Yasuga H, Miki N · 2017 19th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS)

Uses OSTE with tunable, grafted surface energy to miniaturize self-generated 2D droplet arrays formed by oil-water replacement.

Sandström N, Shafagh RZ, Gylfason KB, Haraldsson T, van der Wijngaart W · Journal of Micromechanics and Microengineering

Batch reaction injection molding of OSTE+ microfluidic parts plus direct, unassisted bonding to package QCM sensors into disposable polymer cartridges suited for point-of-care use.

Liu W, Li Y, Ding X · Biofabrication

Combines 3D printing and soft lithography of two OSTE formulations with different surface groups to create patterns where cells adhere only to selected regions.

de Campos RPS, Campos CDM, Almeida GB, da Silva JAF · IEEE Transactions on Biomedical Circuits and Systems

Characterizes OSTE compositions for microchip electrophoresis: sealing, surface homogeneity, wettability, low sorption of non-polar compounds and electroosmotic flow.

Yassin Z · MSc thesis, KTH Royal Institute of Technology

KTH MSc thesis characterizing OSTE-based polymers for acoustofluidic applications.

Fernández R, García P, García M, García J, Jiménez Y, Arnau A · Sensors

150 MHz high-fundamental-frequency QCM biosensor; the flow cell uses a custom OSTEMER Flex gasket to form a 0.53 µL chamber over the sensor.

Hoffmann C, Pinelo M, Woodley JM, Daugaard AE · Biotechnology Progress

Modular OSTE-based screening platform offering many surface chemistries for rapid testing of enzyme immobilization strategies, shown with horseradish peroxidase.

Chen TF, Siow KS, Ng PY, Majlis BY · Materials Science and Engineering: C

Shows that Ar and N2 plasma treatment raises surface energy and functionality of PUMA and OSTE-80, making the surfaces support endothelial (HUVEC) adhesion and proliferation.

Lee HC, Ejserholm F, Gaire J, Currlin S, Schouenborg J, et al. · Journal of Neural Engineering

Uses OSTE+ probes of different stiffness to test whether more flexible implants reduce the brain's foreign-body response, finding a limit below which extra softness gives little benefit.

Marinins A, Zandi Shafagh R, van der Wijngaart W, Haraldsson T, Linnros J, et al. · ACS Applied Materials & Interfaces

Si nanocrystals in a thiol-ene (OSTE) matrix reach ~65% photoluminescence quantum yield, and the polymer's reactivity allows glass lamination for light-conversion layers.

Çakmakçi E, Yuce-Dursun B, Demir S · Reactive and Functional Polymers

Functionalizes OSTE-based coatings with maleic anhydride via thiol-ene click chemistry to covalently immobilize xylanase, improving enzyme stability.

Sticker D, Lechner S, Jungreuthmayer C, Zanghellini J, Ertl P · Analytical Chemistry

Lab-on-chip that mechanically wounds defined circular areas in confluent cell layers for reproducible, automated migration and wound-healing assays.

Hoffmann C · Doctoral thesis, Technical University of Denmark (DTU)

DTU PhD thesis on polymer surface modification for enzyme immobilization, starting from an OSTE-based screening platform.

Chen S · MSc thesis, KTH Royal Institute of Technology

KTH thesis on OSTEmer biostickers for multiplexed microarrays, from polymer fabrication to bioanalysis.

Shafagh RZ, van der Wijngaart W, Haraldsson T · 2017 IEEE 30th International Conference on Micro Electro Mechanical Systems (MEMS)

'NanoRIM': first reaction-injection-molding replication of thermosets with features down to 250 nm, combining cm-scale and sub-µm features in OSTE parts.

Zhou XC · Doctoral thesis, KTH Royal Institute of Technology

Zhou's KTH PhD thesis on OSTE technologies for cell encapsulation and biomolecular analysis.

Marinins A · Doctoral thesis, KTH Royal Institute of Technology

KTH PhD thesis on polymer photonic integrated circuit components, including Si quantum dots encapsulated in OSTE with high quantum yield.

Rahiminejad S, Hansson J, Kohler E, van der Wijngaart W, Haraldsson T, et al. · 2017 IEEE 30th International Conference on Micro Electro Mechanical Systems (MEMS)

First RF-MEMS components in OSTE: gold-coated ridge gap resonators made by direct high-aspect-ratio photostructuring outside the cleanroom perform on par with silicon, SU-8 and CNT versions.

Decrop D, Pardon G, Brancato L, Kil D, Zandi Shafagh R, et al. · ACS Applied Materials & Interfaces

Single-step imprinting of hydrophilic-in-hydrophobic femtolitre microwell arrays in a surface-energy-replicating thiol-ene formulation, enabling digital bead-based bioassays with attomolar detection limits.

Vastesson A · Doctoral thesis, KTH Royal Institute of Technology

Vastesson's KTH PhD thesis on thiol-ene and thiol-ene-epoxy polymers for biomedical microdevices.

Jönsson A, Svejdal RR, Bøgelund N, Nguyen TTTN, Flindt H, et al. · Analytical Chemistry

Off-stoichiometric thiol-ene serves as both chip material and monolithic support for immobilized pepsin, giving digestion efficiency comparable to commercial columns for LC-MS peptide mapping.

Zhou XC, Sjöberg R, Druet A, Schwenk JM, van der Wijngaart W, et al. · Lab Chip

A thiol-ene-epoxy dual-cure resin forms microfluidic gaskets that bond at low temperature to protein microarray surfaces while preserving their biological activity, improving assay transport.

Gómez-Morales J, González-Ramírez LA, Verdugo-Escamilla C, Rodríguez-Ruiz I, Falini G · Key Engineering Materials

Extends sitting-drop vapour diffusion to deposit thin calcium phosphate/apatite layers on OSTE+ films (and graphene) for potential implant coatings.

Chen TF, Siow KS, Ng PY, Nai MH, Lim CT, Yeop Majlis B · Journal of Applied Polymer Science

Argon and nitrogen plasma treatment of PUMA and OSTE-80 introduces polar nitrogen groups; the study follows hydrophobic recovery and chemistry during 15 days of air ageing.

Ejserholm F · Doctoral thesis, Lund University

Lund PhD thesis on developing polymer (OSTE+) neural probes that minimize tissue response.

Martin A, Teychené S, Camy S, Aubin J · Microfluidics and Nanofluidics

Low-cost prototyping route for optically transparent, pressure-resistant chips: UV-cured OSTE+ chemically bonded to glass withstands at least 200 bar without cleanroom processing (summary based on indexed abstract snippets).

Rajabi M, Roxhed N, Shafagh RZ, Haraldson T, Fischer AC, et al. · PLOS ONE

Flexible, stretchable microneedle patches: steel microneedles fixed in a molded, covalently bonded OSTEMER Flex base for conformal skin contact.

Hansson J · Doctoral thesis, KTH Royal Institute of Technology

Hansson's KTH PhD thesis on polymer lab-on-chip systems for sepsis diagnosis, autonomous tests and dried blood spots, including OSTE-based components.

Carlborg CF, Haraldsson T · US Patent 9,523,019 B2 (granted 2016-12-20; priority 2012-05-07; assignee Mercene Labs AB)

Mercene Labs patent on dual-cure thiol-ene-epoxide primer/coating formulations that stay reactive after the first cure so later layers bond covalently (continuation US9862857B2).

Rahiminejad S · Doctoral thesis, Chalmers University of Technology

Chalmers PhD thesis on microsystem technology for >100 GHz components; the full text covers polymer (OSTE) ridge-gap devices (per full-text index).

Hillmering M, Pardon G, Vastesson A, Supekar O, Carlborg CF, et al. · Microsystems & Nanoengineering

Uses confocal Raman mapping to explain why highly off-stoichiometric thiol-enes photostructure more sharply than stoichiometric ones: diffusion of monomers across the mask edge depletes the unexposed zone and limits feature broadening.

Rojas JP, Singh D, Conchouso D, Arevalo A, Foulds IG, Hussain MM · Nano Energy

Stretchable thermoelectric generators combining Bi2Te3/Sb2Te3 with OSTE (and other) substrates in a helical architecture for over 100% stretchability.

Hansson J, Yasuga H, Haraldsson T, van der Wijngaart W · Lab on a Chip

Introduces 'synthetic microfluidic paper': slanted, interlocked OSTE micropillars made by multidirectional lithography, giving high porosity and surface area without capillary collapse. A MEMS 2015 conference version exists (doi:10.1109/memsys.2015.7050873).

Ejserholm F, Stegmayr J, Bauer P, Johansson F, Wallman L, et al. · Biomaterials Research

Toxicity and biocompatibility testing of OSTE+ (up to 100x more flexible than polyimide) for neural implants.

Guo M, Vastesson A, Carlborg CF, Haraldsson T, van der Wijngaart W · MicroTAS 2015 (19th Int. Conf. on Miniaturized Systems for Chemistry and Life Sciences)

Encapsulates nanolitre and picolitre liquid volumes in OSTEMER 322 wells by room-temperature transfer bonding of thin gold films to surface thiols, enabling leak-free long-term storage.

Carlborg CF, Haraldsson T, Öberg K, Malkoch M · US Patent 8,927,664 B2 (granted 2015-01-06; priority 2010-10-01; assignee Mercene Labs AB)

Mercene Labs patent covering articles made from off-stoichiometric thiol-ene mixtures whose leftover thiol or ene groups are later used to covalently bond or modify the part (family includes WO2012042059A1).

Sticker D, Rothbauer M, Lechner S, Hehenberger MT, Ertl P · Lab on a Chip

Evaluates OSTEMER 322 for multilayer, membrane-integrated organ-on-chip devices: optical clarity, vapour permeability, wettability and biocompatibility with several cell types.

Mazurek P, Daugaard AE, Skolimowski M, Hvilsted S, Skov AL · RSC Advances

Uses a dual-cure thiol-ene/thiol-epoxy formulation to make covalently bonded flow-focusing chips with tailored surfaces, and applies them to produce monodisperse liquid-core PDMS microcapsules.

Sandström N, Shafagh RZ, Vastesson A, Carlborg CF, van der Wijngaart W, Haraldsson T · Journal of Micromechanics and Microengineering

OSTE+RIM: reaction injection molding of intermediately cured OSTE+ parts with reactive surfaces, followed by direct covalent bonding and final cure to complete microfluidic devices at scale.

Decrop D, Pardon G, Kokalj T, Puers R, Haraldsson T, et al. · 2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS)

A modified OSTE+ that inherits the surface energy of its mold enables single-step stamp molding of hydrophilic-in-hydrophobic femtolitre microwell arrays.

Tähkä SM, Bonabi A, Nordberg ME, Kanerva M, Jokinen VP, Sikanen TM · Journal of Chromatography A

Compares stoichiometric and 50% allyl-excess thiol-ene chips for microchip electrophoresis, showing how curing and ageing affect surface charge, wetting and separations.

Sharma N, Keshmiri H, Zhou X, Wong TI, Petri C, et al. · The Journal of Physical Chemistry C

Tunable plasmonic nanohole arrays on a thermoresponsive hydrogel cushion; OSTEmer 321 serves as the transparent support for template-stripped gold films.

Heikkinen J · MSc thesis, Aalto University

Aalto MSc thesis (Finnish) characterizing OSTE, OSTE+ and nanocrystalline carbon for neuronal compatibility and fabricating neuron-stimulation devices.

Hansson J, Yasuga H, Basak S, Carlborg CF, van der Wijngaart W, Haraldsson T · MicroTAS 2014 (18th Int. Conf. on Miniaturized Systems for Chemistry and Life Sciences)

Introduces a rubbery OSTE+ formulation suitable for direct lithography, reaching 1:8 aspect-ratio pillars and demonstrating pneumatic pinch valves with a hydrophilic surface.

Burke JM, Pandit KR, Goertz JP, White IM · Biomicrofluidics

Soft-lithography with a rigid thiol-ene (OSTEMER) material yields stiff micro-pillar structures and a simple bonding method, applied to a continuous-flow mechanical cell-lysis device.

Pardon G · Doctoral thesis, KTH Royal Institute of Technology

Pardon's KTH PhD thesis on electrokinetic transport and surface control, including OSTE fabrication and surface-energy methods.

Carlborg CF, Vastesson A, Liu Y, van der Wijngaart W, Johansson M, Haraldsson T · Journal of Polymer Science Part A: Polymer Chemistry

Introduces a UV/UV two-stage curing scheme for OSTE+ and characterizes mechanical properties, conversion, water uptake and hydrolytic/thermal stability at each stage.

Hansson J, Karlsson JM, Carlborg CF, van der Wijngaart W, Haraldsson T · 2014 IEEE 27th International Conference on Micro Electro Mechanical Systems (MEMS)

Benchmarks a rubbery OSTE+ against PDMS for pneumatic microvalves: over 90% lower gas permeability, negligible absorption of dissolved molecules, room-temperature layer bonding and similar valve performance at higher pressures.

Zhou X, Haraldsson T, van der Wijngaart W · MicroTAS 2014 conference paper (ResearchGate DOI)

Single-step reaction injection molding of OSTE+ chips with monolithically integrated internally threaded fluidic ports, vias and channels using a deformable mold.

Haraldsson T, Carlborg CF, van der Wijngaart W · SPIE Proceedings

Overview by the inventors of the OSTE polymer system and its two-step thiol-ene/epoxy cure, framed as a standard material bridging lab-on-chip research and healthcare products.

Hillmering M · Doctoral thesis, KTH Royal Institute of Technology

KTH licentiate thesis on polymer microfluidic sample preparation for bacterial detection in sepsis diagnostics.

Pardon G, Saharil F, Karlsson JM, Supekar O, Carlborg CF, et al. · Microfluidics and Nanofluidics

Presents a mold-free way to make OSTE microfluidic devices by direct photostructuring, combined with robust, spatially directed surface modifications of the channels.

Pardon G, Haraldsson T, van der Wijngaart W · 2014 IEEE 27th International Conference on Micro Electro Mechanical Systems (MEMS)

Discovers that an OSTE formulation with hydrophilic and hydrophobic monomers inherits the surface energy pattern of the mold during curing, allowing one-step structuring and wettability patterning.

Forsberg F, Saharil F, Haraldsson T, Roxhed N, Stemme G, et al. · Journal of Micromechanics and Microengineering

Blister tests compare adhesion energies of OSTE+, a nano-imprint resist and BCB in adhesive wafer bonding; related MEMS 2013 paper (doi:10.1109/memsys.2013.6474248) first demonstrated OSTE(+) as a low-temperature wafer-bonding adhesive.

Ejserholm F, Vastesson A, Haraldsson T, van der Wijngaart W, Schouenborg J, et al. · 2013 6th International IEEE/EMBS Conference on Neural Engineering (NER)

OSTE+ neural probe whose stiffness drops from ~1.9 GPa at 10 °C to ~30 MPa at 40 °C, rigid for insertion yet soft in tissue.

Errando-Herranz C, Vastesson A, Zelenina M, Pardon G, Bergström G, et al. · MicroTAS 2013 (17th Int. Conf. on Miniaturized Systems for Chemistry and Life Sciences, Freiburg)

First cell-viability data on OSTE: three formulations tested, with viability depending on thiol excess and one formulation supporting proliferation.

Saharil F, Forsberg F, Liu Y, Bettotti P, Kumar N, et al. · Journal of Micromechanics and Microengineering

Two transfer-bonding schemes for integrating fragile nanoporous inorganic membranes into microdevices using OSTE(+): soft and tacky after the first cure, it bonds at room temperature and stiffens to ~1.2 GPa after the second cure. Journal version of the MEMS 2012 work.

Sikanen TM, Lafleur JP, Moilanen ME, Zhuang G, Jensen TG, Kutter JP · Journal of Micromechanics and Microengineering

Characterizes bonding of thiol-ene microchips while varying thiol/allyl ratio from 2:1 to 1:2; allyl-excess and stoichiometric layers were stiffer and held up to 6 bar.

Errando-Herranz C, Saharil F, Romero AM, Sandström N, Shafagh RZ, et al. · Optics Express

Single-step molding/photopatterning of an OSTE fluidic layer with vias and connectors, followed by unassisted dry bonding to a grating-coupled silicon photonic ring-resonator sensor; wafer-level compatible packaging. A Transducers 2013 conference version also exists.

Saharil F, Ahlford A, Kuhnemund M, Skolimowski M, Conde A, et al. · 2013 Transducers & Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS & EUROSENSORS XXVII)

Ligation-based mutation detection and rolling-circle amplification run directly in unmodified OSTE+ chambers without bubble problems or enzyme inhibition, outperforming PMMA and PDMS.

Bou SJMC, Ellis AV · SPIE Proceedings

Fabricates microfluidic devices from three OSTE formulations (30% allyl excess, 50% and 90% thiol excess) and characterizes their surface functional groups by FTIR and solid-state NMR.

Lafleur JP, Kwapiszewski R, Jensen TG, Kutter JP · The Analyst

Rapid one-step photochemical patterning of biomolecules on thiol-ene chips whose surfaces carry excess thiol groups (the off-stoichiometry principle).

Vastesson A, Zhou X, Sandstrom N, Saharil F, Supekar O, et al. · 2013 Transducers & Eurosensors XXVII: The 17th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS & EUROSENSORS XXVII)

First use of direct photolithography in dual-cure OSTE+ to build a microdevice: 1:10 aspect-ratio pillars in 2 mm thick layers and a three-layer device assembled by adhesive-free dry bonding.

Saharil F, Carlborg CF, Haraldsson T, van der Wijngaart W · Lab on a Chip

'Click' wafer bonding: thiol-rich OSTE microstructures bond rapidly and void-free to silicon wafers functionalized with common bio-linkers, enabling biocompatible wafer-level assembly of lab-on-chip devices.

Saharil F, Gylfason KB, Liu Y, Haraldsson T, Bettotti P, et al. · 2012 IEEE 25th International Conference on Micro Electro Mechanical Systems (MEMS)

Adhesive-free, low-temperature transfer bonding of fragile porous-silicon membranes into OSTE+ microfluidic devices, exploiting the epoxy's reactivity toward almost any dry surface.

Vastesson A · MSc thesis, Linköping University

Linköping MSc thesis micro-structuring OSTE materials combined with electronic polymers for cell interfaces.

Carlborg F, Moraga F, Saharil F, van der Wijngaart W, Haraldsson T · MicroTAS 2012 (16th Int. Conf. on Miniaturized Systems for Chemistry and Life Sciences)

Photografting of methacrylates onto unreacted thiols in OSTE channels creates permanent, patterned hydrophilic/hydrophobic regions (contact angles 20-115°) that remain stable for months.

Saharil F, Fissi LE, Liu Y, Calborg F, Vandormael D, et al. · MicroTAS 2012 (16th Int. Conf. on Miniaturized Systems for Chemistry and Life Sciences)

Introduces dual-cure OSTE+ for heterogeneous lab-on-chips and shows leak-free dry bonding to nine different substrate materials while retaining thermoplastic-like final stiffness.

Carlborg CF, Haraldsson T, Öberg K, Malkoch M, van der Wijngaart W · Lab on a Chip

The founding OSTE paper: introduces off-stoichiometry thiol-ene formulations as a rapid-prototyping alternative to PDMS, showing tunable stiffness, built-in surface anchors for one-step surface modification and leak-free direct UV bonding of replica-molded chips.

Carlborg CF, Cretich M, Haraldsson T, Solá L, Bagnati M, et al. · MicroTAS 2011 (15th Int. Conf. on Miniaturized Systems for Chemistry and Life Sciences)

'Biosticker': patterned OSTE microfluidic stickers that bond reversibly and biocompatibly to spotted microarrays, demonstrated for flow-through protein and DNA hybridization assays.

Carlborg CF · Doctoral thesis, KTH Royal Institute of Technology

Carlborg's KTH doctoral thesis, which developed the OSTE polymer platform together with new surface and manufacturing methods aimed at point-of-care microfluidic tests.

Liu Y · MSc thesis, Luleå University of Technology

MSc thesis (Luleå University of Technology, DiVA) that developed the dual-cure thiol-ene-epoxy system (early OSTE+), raising glass transition temperature for heated applications such as PCR and enabling bonding and surface modification.

Carlborg CF, Saharil F, Haraldsson T, van der Wijngaart W · MicroTAS 2011 (15th Int. Conf. on Miniaturized Systems for Chemistry and Life Sciences)

Wafer-scale, low-temperature (<37 °C) covalent dry bonding of OSTE microfluidic layers to silicon for batch packaging of biocompatible lab-on-chip devices.

Sandstrom N, Shafagh RZ, Carlborg CF, Haraldsson T, Stemme G, van der Wijngaart W · 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference

One-step integration of gold-coated sensors (a QCM crystal) into OSTE cartridges: excess surface thiols bond covalently to gold on contact, giving void-free seals tested to 2 bar.